Genetic Testing for Mental Health Medications

If you have ever tried a medication that did not work or caused an adverse reaction, it may be due to genetic incompatibility. Every single one of us has a unique set of DNA that, among many other things, determines how our bodies will react to medications. Technology has advanced to the point where genetic screenings can improve success rates in medications by matching individuals with drugs that they are most compatible with.

Drug-gene testing, also known as pharmacogenomics or pharmacogenetics, is the study of how an individual’s genes affect their body’s response to drugs. By conducting genetic testing for medications, we can take much of the guesswork out of finding the right prescription for our patients. It is smart prescribing for mental health medications.

Based on findings from the STAR*D trial with depression patients, two-thirds of patients will not achieve complete relief from the first medication they try. Psychiatric medications are known to be difficult to match with patients. It can take a significant amount of trial and error to find a good match that produces effective results for the patient. Genetic testing capabilities give us a better chance at successfully matching patients with the right medication the first time.